P21(CAS 57531-37-0 ) – p21 peptide

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P21 – p21 peptide is a bioactive peptide primarily used for its targeted biological effects in pharmaceutical, cosmetic, and research applications, including tissue repair, anti-aging, and therapeutic development.

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  • P21 (CAS 57531-37-0 ) is a high-purity neuroprotective peptide API, featuring ≥99% purity (HPLC-verified) and a modified peptide structure (molecular weight: ~578.3 Da). As a synthetic analog of ciliary neurotrophic factor (CNTF), it activates the CNTF receptor complex without triggering allergic responses—its core mechanism for protecting neurons and enhancing cognitive function.
  • To improve bioavailability, adamantane building blocks are added to its termini, helping it cross the blood-brain barrier (BBB) more efficiently. This lyophilized peptide maintains stable activity under -20℃ storage and is widely used in preclinical research on neurodegenerative diseases (e.g., Alzheimer’s) and cognitive impairment: it rescues synaptic deficits, boosts hippocampal neurogenesis, and reverses cognitive decline in murine models. For pharmaceutical R&D teams, its high purity and BBB penetration make it a reliable raw material for exploring neuroprotective therapies.

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