Colchicine (CAS 64-86-8)/ Anti-Inflammatory

Colchicine (CAS 64-86-8) is a high-purity pharmaceutical API classified as a potent anti-inflammatory agent, featuring a natural alkaloid structure extracted from Colchicum autumnale bulbs. Its core mechanism targets tubulin polymerization, inhibiting microtubule formation to block neutrophil activity and cellular division—delivering rapid anti-inflammatory and pain-relieving effects for gout flares. Unlike conventional anti-inflammatories, it also demonstrates efficacy in treating familial Mediterranean fever and reducing cardiovascular event risks in ASCVD patients.

Presented as a pale yellow crystalline powder with good solubility in ethanol and chloroform, it supports flexible oral dosage form development. It caters to the core needs of anti-inflammatory drug manufacturers, rheumatology therapy developers, and cardiovascular pharmaceutical suppliers. Widely applied in gout flare management, familial Mediterranean fever treatment, and ASCVD secondary prevention, it aligns with demand for multi-indication anti-inflammatory raw materials. Produced under strict GMP standards, each batch undergoes rigorous purity, stability, and bioactivity testing to meet international pharmacopoeia requirements, ensuring consistency for clinical use.