Clomipramine (CAS 303-49-1) – Antidepressant Tricyclic OCD API

Clomipramine (CAS 303-49-1) is a high-purity pharmaceutical API, a classic tricyclic antidepressant with potent 5-HT and norepinephrine reuptake inhibition. Its dihydrodibenzazepine structure selectively blocks neurotransmitter reuptake, with stronger affinity for 5-HT transporters—delivering both antidepressant and anti-anxiety effects, while exerting specific efficacy for obsessive-compulsive disorder (OCD). Unlike many modern antidepressants, it covers multiple indications, including chronic pain and narcoleptic cataplexy.

As a white or pale yellow crystalline powder, it is highly soluble in water and ethanol, suitable for oral tablets, capsules, and injections. It meets the core needs of neuropsychiatric drug manufacturers, mood disorder therapy developers, and clinical supply chains. Widely used for various depressive states, OCD, phobias, and panic disorders, it is also effective for childhood nocturnal enuresis (over 5 years old) and chronic pain syndromes. Produced under strict GMP standards, each batch undergoes rigorous purity, stability, and neurotransmitter inhibition testing to meet international pharmacopoeia requirements, ensuring consistent clinical performance.