B7-33(CAS 1818415-56-3)Vasodilation,Blood pressure reduction Peptides

B7-33 is a revolutionary, highly selective single-chain RXFP1 (relaxin family peptide receptor 1) agonist. Engineered as a cutting-edge functional fragment of native human relaxin-2 (H2-relaxin), it exerts profound anti-fibrotic and tissue-remodeling therapeutic variations. Unlike full-length relaxin, B7-33 specifically up-regulates matrix metalloproteinases (MMPs) to degrade excess collagen while effectively suppressing TGF-$\beta$-induced fibroblast activation. It is designed to reverse aberrant fibrosis across multiple organ systems—including the heart, lungs, kidneys, and skin—promoting functional tissue regeneration and scar-free healing without triggering unwanted vasodilatory side effects.