ARA290 (Cibinetide)CAS 1208243-50-8 Neuroprotection Peptides

ARA290 (Cibinetide) is a revolutionary 11-amino-acid synthetic peptide modeled from the tertiary structure of erythropoietin (EPO). Operating through a non-erythropoietic pathway, it selectively activates the Innate Repair Receptor (IRR) to deliver potent tissue-protective benefits without stimulating red blood cell production—thereby eliminating traditional EPO-related cardiovascular risks. ARA290 is engineered to down-regulate hyperactive immune responses, suppress pro-inflammatory cytokines, and significantly alleviate debilitating neuropathic pain associated with small fiber neuropathy (SFN). Furthermore, it actively promotes axonal repair and small nerve fiber regeneration, demonstrating profound potential in reversing neurodegenerative damage and enhancing metabolic control.